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What type of enzyme catalyzes the intramolecular shift of a chemical group?


A) hydrolase
B) kinase
C) dehydrogenase
D) mutase
E) None of the above.

F) A) and E)
G) A) and C)

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D

What are glucose transporters and how do the different types of transporters differ?

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Glucose transporters mediate the thermod...

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Choose the correct answer from the list below. Not all of the answers will be used. -____________ is the enzyme responsible for converting galactose to be used in the glycolytic pathway.


A) obligate anaerobes
B) AMP
C) pyruvate
D) NAD+
E) glucose
F) UDP-glucose
G) GLUT5
H) facultative anaerobes
I) ATP
J) magnesium
K) galactokinase
L) GLUT2
M) galactose isomerase

N) A) and B)
O) C) and H)

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Glycolysis produces a net of ______________ moles of ATP per 1 mole of glucose.

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Why is glucose the most stable hexose?

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The hydroxyl groups and the hy...

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In the absence of oxygen, ______________ increases the expression of most glycolytic enzymes and the glucose transporters GLUT1 and GLUT3.

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HIF-1, or ...

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Choose the correct answer from the list below. Not all of the answers will be used. -____________ is the principle carbohydrate in living systems.


A) obligate anaerobes
B) AMP
C) pyruvate
D) NAD+
E) glucose
F) UDP-glucose
G) GLUT5
H) facultative anaerobes
I) ATP
J) magnesium
K) galactokinase
L) GLUT2
M) galactose isomerase

N) B) and D)
O) E) and I)

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How is glycolysis maintained under anaerobic conditions?

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Pyruvate can be reduced to eit...

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A potent allosteric activator of liver phosphofructokinase is ______________, which is produced from fructose-6-phosphate by PFK2.

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fructose-2...

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In alcoholic fermentation, the decarboxylation of pyruvate requires a coenzyme that contains the vitamin ______________.

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Describe the biochemical explanation for galactosemia.

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Galactose is metabolized by conversion t...

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Choose the correct answer from the list below. Not all of the answers will be used. -The intermediate that is necessary for the conversion of galactose to glucose is ____________.


A) obligate anaerobes
B) AMP
C) pyruvate
D) NAD+
E) glucose
F) UDP-glucose
G) GLUT5
H) facultative anaerobes
I) ATP
J) magnesium
K) galactokinase
L) GLUT2
M) galactose isomerase

N) C) and F)
O) A) and C)

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What is the function of glyceraldehyde 3-phosphate dehydrogenase?


A) oxidation by NAD+ and the formation of acyl phosphate
B) oxidation of the alcohol to an aldehyde
C) dehydration and dephosphorylation of GAP
D) hydrolysis of GAP
E) None of the above.

F) B) and E)
G) A) and D)

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A

Glucose is the most stable hexose because the hydroxyl groups are all in the ______________position.

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Choose the correct answer from the list below. Not all of the answers will be used. -____________: These organisms cannot survive in the presence of oxygen.


A) obligate anaerobes
B) AMP
C) pyruvate
D) NAD+
E) glucose
F) UDP-glucose
G) GLUT5
H) facultative anaerobes
I) ATP
J) magnesium
K) galactokinase
L) GLUT2
M) galactose isomerase

N) F) and H)
O) C) and G)

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What reaction is catalyzed by aldolase?


A) isomerization of DHAP to GAP
B) ligation of GAP and DHAP
C) reversible cleavage of F-1,6-BP to DHAP and GAP
D) cleavage of DHAP to GAP
E) irreversible aldol condensation of DHAP and GAP

F) A) and E)
G) A) and B)

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Why is it important that the glycolytic and gluconeogenic pathways are reciprocally regulated?

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Glycolysis is stimulated when the energy...

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Which two 3-carbon molecules are generated by the cleavage of fructose-1,6-bisphosphate?


A) glyceraldehyde-3-phosphate and 3-phosphoglycerate
B) glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
C) pyruvate and phosphoenolpyruvate
D) enolase and 2-phosphoglycerate
E) glyceraldehyde-3-phosphate and pyruvate

F) C) and D)
G) A) and C)

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What is the function of a thioester intermediate such as the one formed from GAP?


A) It speeds up the actual reaction so that more product can be made.
B) The thioester shifts the equilibrium of the first stage of the reaction.
C) The thioester allows the two-step reaction to be coupled so the second reaction, the energetically unfavorable phosphorylation, can proceed.
D) The thioester intermediate induces a conformational change that alters the enzyme specificity.
E) The thioester prevents the formation of metabolically unfavorable side products.

F) C) and D)
G) B) and E)

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How are the glycolytic enzymes regulated?


A) through transcriptional control
B) through reversible phosphorylation
C) through allosteric control
D) All of the above.
E) None of the above.

F) A) and E)
G) A) and C)

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D

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